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srfAA

surfactin synthetase A
genesrfAA
locusRBAM_003650
feature typeCDS
productABS72764.1 surfactin non-ribosomal peptide synthetase SrfAA
synonymscomL
homologBSU03480
start342619
stop353373
direction+
length10755
essentialno
protein detected in LByes
Genomic Context

Functional category containing this gene/protein

CategoryMetabolism
Subcategory1additional metabolic pathways
Subcategory2miscellaneous metabolic pathways
Subcategory3biosynthesis of antibacterial compounds

Phenotypes of a mutant

plant-bacteria interaction

biocontrol by induced systemic resistance against plant pathogens

Expression and Regulation

Operons
srfAA-srfAB-comS-srfAC-srfAD
Transcripts
Primary TSS342354
Secondary TSS
Internal TSS351687
Antisense TSS346516

Sigma factors

SigA

Protein regulator

Abh repression CodY repression ComA activation PerR activation PhoP activation Spx repression

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

PerR Regulon
The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Refer to BSU03480
Structure
Refer to BSU03480
Malonylation
Acetylation
"K320,793,1765,2161"
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Chen,X.H., Vater,J., Piel,J., Franke,P., Scholz,R

Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.

J Bacteriol. 2006 Jun;188(11):4024-36;PMID:16707694

Koumoutsi A, Chen XH, Henne A, Liesegang H, Hitze

Structural and functional characterization of gene clusters directing nonribosomal synthesis of bioactive cyclic lipopeptides in Bacillus amyloliquefaciens strain FZB42.

J Bacteriol. 2004 Feb;186(4):1084-96;PMID:14762003