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dfnA

ACP S-malonyltransferase involved in difficidin synthesis DfnA
genedfnA
locusRBAM_022080
feature typeCDS
productABS74569.1 ACP S-malonyltransferase
synonyms
homolog
start2344012
stop2346270
direction-
length2259
essential
protein detected in LBnot detected
Genomic Context

Functional category containing this gene/protein

Category
Subcategory1
Subcategory2
Subcategory3

Phenotypes of a mutant

plant-bacteria interaction

control of plant pathogens

Expression and Regulation

Operons
Transcripts
Primary TSS2346478
Secondary TSS
Internal TSS
Antisense TSS2345388

Sigma factors

Protein regulator

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

The protein


Catalyzed reaction/ biological activity
E.C. number
2.3.1.39
Protein family
https://enzyme.expas
Domains
Effectors of protein activity
Structure
Malonylation
"K169,641"
Acetylation
K616
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Goodson JR, Klupt S, Zhang C, Straight P, Winkler

LoaP is a broadly conserved antiterminator protein that regulates antibiotic gene clusters in Bacillus amyloliquefaciens.

Nat Microbiol. 2017 Feb 13;2:17003. doi: 10.1038/nmicrobiol.2017.3.;PMID:28191883

Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Chen,X.H., Vater,J., Piel,J., Franke,P., Scholz,R

Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.

J Bacteriol. 2006 Jun;188(11):4024-36;PMID:16707694