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bacB

isomerase component of bacilysin synthetase
genebacB
locusRBAM_034920
feature typeCDS
productABS75821.2 cupin domain-containing protein
synonymsywfC
homologBSU37730
start3598466
stop3599176
direction-
length714
essential
protein detected in LByes
Genomic Context

Functional category containing this gene/protein

CategoryMetabolism
Subcategory1additional metabolic pathways
Subcategory2miscellaneous metabolic pathways
Subcategory3biosynthesis of antibacterial compounds

Phenotypes of a mutant

plant-bacteria interaction

biocontrol action: antibacterial bacilysin acts against several plant pathogens and cyanobacterial bloom in freshwater

Expression and Regulation

Operons
bacA-bacB-bacC-bacD-bacE-bacF
Transcripts
Primary TSS
Secondary TSS
Internal TSS3598989
Antisense TSS

Sigma factors

SigA

Protein regulator

AbrB repression CodY repression ScoC repression

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

SigA Regulon
The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Refer to BSU37730
Structure
Refer to BSU37730
Malonylation
Acetylation
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Wu L, Wu H, Chen L, Lin L, Borriss R, Gao X.

Bacilysin overproduction in Bacillus amyloliquefaciens FZB42 markerless derivative strains FZBREP and FZBSPA enhances antibacterial activity.

Appl Microbiol Biotechnol. 2015 May;99(10):4255-63. doi: 10.1007/s00253-014-6251-0. Epub 2014 Dec 4.;PMID:25472439

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540